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Anti-MMP-9 Polyclonal Antibody 3

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货号 TMAB-01159

别名 MMP-9, MANDP2, GELB, Gelatinase B, CLG4B

Anti-MMP-9 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 MMP-9。Anti-MMP-9 Polyclonal Antibody 3 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

Anti-MMP-9 Polyclonal Antibody 3

Anti-MMP-9 Polyclonal Antibody 3

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Rating icon 还可以
货号 TMAB-01159 别名 MMP-9, MANDP2, GELB, Gelatinase B, CLG4B

Anti-MMP-9 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 MMP-9。Anti-MMP-9 Polyclonal Antibody 3 可用于 ELISA,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-MMP-9 Polyclonal Antibody 3 is a Rabbit antibody targeting MMP-9. Anti-MMP-9 Polyclonal Antibody 3 can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
别名MMP-9, MANDP2, GELB, Gelatinase B, CLG4B
Ig Type
IgG
反应种属
Human
验证活性
1. 25 μg total protein per Lane of various lysates probed with MMP9 polyclonal antibody, unconjugated (TMAB-01159) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Lung Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP9 Polyclonal Antibody, Unconjugated (TMAB-01159) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP9 Polyclonal Antibody, Unconjugated (TMAB-01159) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP9 Polyclonal Antibody, Unconjugated (TMAB-01159) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP9 Polyclonal Antibody, Unconjugated (TMAB-01159) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Gastric Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MMP9 Polyclonal Antibody, Unconjugated (TMAB-01159) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用ELISAIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted; extracellular space; extracellular matrix.
组织特异性Produced by normal alveolar macrophages and granulocytes. Post-translational modifications : Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human MMP9
抗原种属
Human
基因名称
Mmp9
基因ID
蛋白名称
Matrix metalloproteinase-9
Uniprot ID
研究领域
MMP,Protease inhibitors ELISA kits,Cancer proteins ELISA kits,Atherosclerotic proteins ELISA kits,MMPs,Thrombosis,MMP,MMPs,MMPs,MMPs
功能
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly- -Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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