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Anti-Carbonic Anhydrase 9 Antibody (7K666)

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产品编号 TMAY-03392

Anti-Carbonic Anhydrase 9 Antibody (7K666) 是一种 Rabbit 抗体,靶向 Carbonic Anhydrase 9。Anti-Carbonic Anhydrase 9 Antibody (7K666) 可用于 IHC-P。

Anti-Carbonic Anhydrase 9 Antibody (7K666)

Anti-Carbonic Anhydrase 9 Antibody (7K666)

Rating icon 还可以
产品编号 TMAY-03392

Anti-Carbonic Anhydrase 9 Antibody (7K666) 是一种 Rabbit 抗体,靶向 Carbonic Anhydrase 9。Anti-Carbonic Anhydrase 9 Antibody (7K666) 可用于 IHC-P。

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产品介绍

生物活性
产品描述
Anti-Carbonic Anhydrase 9 Antibody (7K666) is a Rabbit antibody targeting Carbonic Anhydrase 9. Anti-Carbonic Anhydrase 9 Antibody (7K666) can be used in IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
7K666
交叉反应
Mouse
验证活性
Immunochemical staining of mouse CAR9 in mouse stomach (from 2 donors) with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:250-1:1000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carbonic Anhydrase IX / CAR9 (rM Carbonic Anhydrase IX / CAR9; TMPY-01700; NP_647466.2; Met1-Asp390).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse Carbonic Anhydrase IX / CAR9 protein (TMPY-01700)
抗原种属
Mouse
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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