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CBR-470-2, a glycine-substituted analog, exhibits the capacity to activate NRF2 signaling, making it a valuable compound for investigating glycolysis modulation in scientific research [1].

CBR-470-2, a glycine-substituted analog, exhibits the capacity to activate NRF2 signaling, making it a valuable compound for investigating glycolysis modulation in scientific research [1].
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 2,730 | 5日内发货 | |
| 5 mg | ¥ 3,990 | 5日内发货 | |
| 10 mg | ¥ 6,660 | 5日内发货 |
| 产品描述 | CBR-470-2, a glycine-substituted analog, exhibits the capacity to activate NRF2 signaling, making it a valuable compound for investigating glycolysis modulation in scientific research [1]. |
| 体外活性 | CBR-470-2 (1-10 μM; 24 h) increases transcript levels of the NRF2-responsive genes NQO1 and HMOX1 in epidermal keratinocytes and dermal fibroblasts[1]. |
| 体内活性 | CBR-470-2 (50 mg/kg; p.o. twice daily for 10 d) induces activation of NRF2 signaling in vivo[1]. Animal Model: Balb/C mice (5-week old) are exposed to UVB[1] |
| 分子量 | 402.26 |
| 分子式 | C12H13Cl2NO6S2 |
| CAS No. | 2416095-00-4 |
| 密度 | 1.71 g/cm3 (Predicted) |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| 溶解度信息 | DMSO: 200 mg/mL (497.19 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| 体内实验配方 | 10% DMSO+90% Corn Oil: 5 mg/mL (12.43 mM), Sonication is recommeded. 请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。 | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
对于不同动物的给药剂量换算,您也可以参考 更多