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顶部生物活性储存和溶解信息计算器

Anti-SOD2 Antibody (1Y900)

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产品编号 TMAC-03819

别名 superoxide dismutase 2, mitochondrial, MVCD6, MNSOD, IPOB

Anti-SOD2 Antibody (1Y900) 是一种 Rabbit 抗体，靶向 SOD2。Anti-SOD2 Antibody (1Y900) 可用于 IHC,WB。

Anti-SOD2 Antibody (1Y900)

Anti-SOD2 Antibody (1Y900)

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产品编号 TMAC-03819 别名 superoxide dismutase 2, mitochondrial, MVCD6, MNSOD, IPOB

Anti-SOD2 Antibody (1Y900) 是一种 Rabbit 抗体，靶向 SOD2。Anti-SOD2 Antibody (1Y900) 可用于 IHC,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-SOD2 Antibody (1Y900) is a Rabbit antibody targeting SOD2. Anti-SOD2 Antibody (1Y900) can be used in IHC,WB.
别名superoxide dismutase 2, mitochondrial, MVCD6, MNSOD, IPOB
Ig Type
IgG
克隆号
1Y900
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of SOD2 on different lysates using anti-SOD2 antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse brain, Lane 2: SH-SY-5Y, Lane 3: Human heart.
2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
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应用IHCWB
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anion. The SOD-2 precursor is a 222 amino acid protein that is encoded by nuclear chromatin, synthesized in the cytosol and imported posttranslationally into the mitochondrial matrix. Unlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer??s disease, Parkinson??s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle. Polymorphisms in the SOD-2 gene have also been implicated in nonfamilial, idiopathic, dilated cardiomyopathy in humans.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P04179
化学信息
分子量Theoretical: 21 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

MVCD-6MVCD 6

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