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Anti-Phospho-E2A (Thr355) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-E2A (Thr355)。Anti-Phospho-E2A (Thr355) Polyclonal Antibody 可用于 IHC。
Anti-Phospho-E2A (Thr355) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-E2A (Thr355)。Anti-Phospho-E2A (Thr355) Polyclonal Antibody 可用于 IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-E2A (Thr355) Polyclonal Antibody is a Rabbit antibody targeting Phospho-E2A (Thr355). Anti-Phospho-E2A (Thr355) Polyclonal Antibody can be used in IHC. |
别名 | p-E2A (Thr355), p-E2A (T355), E2A (p-Thr355), E2A (p-T355) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human brain tissue using E2A (Phospho-Thr355) antibody TMAC-01207 (left) or the same antibody preincubated with blocking peptide (right). |
应用 | |
推荐剂量 | IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of threonine 355 (P-S-T(p)-P-V) derived from Human E2A |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 67 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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