CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.6 kDa and the accession number is Q5QGZ9-2.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,400 | 5日内发货 | ||
500 μg | ¥ 13,600 | 5日内发货 | ||
1 mg | ¥ 22,700 | 5日内发货 |
生物活性 | Immobilized Human CLEC12A at 0.5μg (100μl/Well) on the plate. Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 3.7ng/ml determined by ELISA. |
产品描述 | CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.6 kDa and the accession number is Q5QGZ9-2. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | N-His |
蛋白编号 | Q5QGZ9-2 |
别名 | CLECSF7, CLL-1, PRO34150, CLL1, DLEC, CLEC12A, DCAL2, CLECSF11, MICL, CD303, DCAL-2, HECL, CD371 |
蛋白构建 | His65-Ala265 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | 24.6 kDa (predicted). Due to glycosylation, the protein migrates to 38-55 kDa based on Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. |
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CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His) PRO 34150 CLECSF7 CLECSF 7 CD 303 CLECSF-7 CLL 1 CD 371 CLL-1 PRO34150 CLL1 DLEC CLECSF 11 CD-371 CLEC12A DCAL2 PRO-34150 CLECSF11 MICL CD-303 CD303 DCAL-2 CLECSF-11 HECL CD371 DCAL 2 recombinant recombinant-proteins proteins protein