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Anti-FGFRL1 Antibody (4C661)
还可以产品编号 TMAY-03161
别名 fibroblast growth factor receptor-like 1, FGFR5γ, FGFR5β, FGFR5gamma, FGFR5beta, FGFR5
Anti-FGFRL1 Antibody (4C661) 是一种 Rabbit 抗体，靶向 FGFRL1。Anti-FGFRL1 Antibody (4C661) 可用于 WB,IP。
Anti-FGFRL1 Antibody (4C661)
Anti-FGFRL1 Antibody (4C661)
还可以产品编号 TMAY-03161 别名 fibroblast growth factor receptor-like 1, FGFR5γ, FGFR5β, FGFR5gamma, FGFR5beta, FGFR5
Anti-FGFRL1 Antibody (4C661) 是一种 Rabbit 抗体，靶向 FGFRL1。Anti-FGFRL1 Antibody (4C661) 可用于 WB,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-FGFRL1 Antibody (4C661) is a Rabbit antibody targeting FGFRL1. Anti-FGFRL1 Antibody (4C661) can be used in WB,IP. |
| 别名 | fibroblast growth factor receptor-like 1, FGFR5γ, FGFR5β, FGFR5gamma, FGFR5beta, FGFR5 |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4C661 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Anti-FGFRL1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell Lysate. -Lane B: HepG2 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:55 kDa. -Observed band size:62 kDa. 2. Mouse FGFRL1 was immunoprecipitated using: -Lane A:0.5 mg Hela Whole Cell Lysate. -2 µL anti-Mouse FGFRL1 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-Mouse FGFRL1 rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Clean-Blotô IP Detection Reagent (HRP) at 1:1000 dilution. -Developed using the DAB staining technique. -Performed under reducing conditions. -Predicted band size: 55 kDa. -Observed band size: 70 kDa |
| 应用 | WB,IP |
| 推荐剂量 | WB: 1:500-1:2000; IP: 4-6 μL/mg of lysate |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FGFRL1 / FGFR5 (rM FGFRL1 / FGFR5; TMPY-01360; NP_473412.1; Met1-Pro374). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A unique feature of FGFRL1/FGFR5 is that it does not contain an intracellular tyrosine kinase domain. Some muscle types, including the muscles of the tongue and the diaphragm, express FGFRL1/FGFR5 at relatively high level. In contrast, the heart and the skeletal muscles of the limbs, as well as many other organs (brain, lung, liver, kidney, gut) express Fgfrl1 only at basal level. It is conceivable that FGFRL1/FGFR5 interacts with other Fgfrs, which are expressed in cartilage and muscle, to modulate FGF signaling.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse FGFRL1 / FGFR5 protein (TMPY-01360) |
| 抗原种属 | Mouse |
| 研究领域 | Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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