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Anti-CD160 Antibody-APC (3P845)

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产品编号 TMAY-02275A

Anti-CD160 Antibody-APC (3P845) 是一种 APC-conjugated Rabbit 抗体,靶向 CD160。Anti-CD160 Antibody-APC (3P845) 可用于 FCM。

Anti-CD160 Antibody-APC (3P845)

Anti-CD160 Antibody-APC (3P845)

Rating icon 还可以
产品编号 TMAY-02275A

Anti-CD160 Antibody-APC (3P845) 是一种 APC-conjugated Rabbit 抗体,靶向 CD160。Anti-CD160 Antibody-APC (3P845) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-CD160 Antibody-APC (3P845) is a APC-conjugated Rabbit antibody targeting CD160. Anti-CD160 Antibody-APC (3P845) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
3P845
交叉反应
Human
验证活性
Flow cytometric analysis of Human CD160 expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human CD160. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CD160 (rh CD160; TMPY-01905; NP_008984.1; Met1-Leu158) and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.1% sodium azide
研究背景CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Human CD160 Protein (TMPY-01905)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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