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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HERPUD1 Polyclonal Antibody

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货号 TMAB-06985

Anti-HERPUD1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HERPUD1。Anti-HERPUD1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HERPUD1 Polyclonal Antibody

Anti-HERPUD1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06985

Anti-HERPUD1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HERPUD1。Anti-HERPUD1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-HERPUD1 Polyclonal Antibody is a Rabbit antibody targeting HERPUD1. Anti-HERPUD1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein.
组织特异性Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景HERPUD1 is a includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013].
抗原信息
免疫原
KLH conjugated synthetic peptide: human HERPUD1
抗原种属
Human
基因名称
HERPUD1
基因ID
9709
蛋白名称
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Uniprot ID
Q15011
功能
Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation.
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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