Anti-LTF Antibody (1Z940)

Name: Anti-LTF Antibody (1Z940)
Brand: TargetMol
SKU: TMAH-00710
Rating: 4.5 (1 reviews)

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产品编号 TMAH-00710

别名 LF, HLF2, HEL110, GIG12

Anti-LTF Antibody (1Z940) 是一种抗体，靶向 LTF。Anti-LTF Antibody (1Z940) 可用于 ELISA, IHC。

Anti-LTF Antibody (1Z940)

还可以

产品编号 TMAH-00710 别名 LF, HLF2, HEL110, GIG12

Anti-LTF Antibody (1Z940) 是一种抗体，靶向 LTF。Anti-LTF Antibody (1Z940) 可用于 ELISA, IHC。

规格	价格	库存	数量
50 μL	¥ 1,300	5日内发货
100 μL	¥ 2,180	5日内发货

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产品描述	Anti-LTF Antibody (1Z940) is an antibody targeting LTF. Anti-LTF Antibody (1Z940) can be used in ELISA, IHC.
别名	LF, HLF2, HEL110, GIG12
Ig Type	Rabbit IgG
克隆号	1Z940
交叉反应	Human
验证活性	IHC image of TMAH-00710 diluted at 1:100 and staining in paraffin-embedded human salivary gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
应用	ELISA, IHC
推荐剂量	IHC:1:50-1:200.
抗体种类	Monoclonal
亚细胞定位	[Isoform 1]: Secreted. Cytoplasmic granule. Note=Secreted into most exocrine fluids by various endothelial cells. Stored in the secondary granules of neutrophils.; [Isoform DeltaLf]: Cytoplasm. Nucleus. Note=Mainly localized in the cytoplasm.
构建方式	Recombinant Antibody
纯化方式	Affinity-chromatography
性状	Liquid
缓冲液	Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景	Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Major iron-binding and multifunctional protein found in exocrine fluids such as breast milk and mucosal secretions. Has antimicrobial activity, which depends on the extracellular cation concentration. Antimicrobial properties include bacteriostasis, which is related to its ability to sequester free iron and thus inhibit microbial growth, as well as direct bactericidal properties leading to the release of lipopolysaccharides from the bacterial outer membrane. Can also prevent bacterial biofilm development in P.aeruginosa infection. Has weak antifungal activity against C.albicans. Has anabolic, differentiating and anti-apoptotic effects on osteoblasts and can also inhibit osteoclastogenesis, possibly playing a role in the regulation of bone growth. Promotes binding of species C adenoviruses to epithelial cells, promoting adenovirus infection. Can inhibit papillomavirus infections. Stimulates the TLR4 signaling pathway leading to NF-kappa-B activation and subsequent pro-inflammatory cytokine production while also interfering with the lipopolysaccharide (LPS)-stimulated TLR4 signaling. Inhibits neutrophil granulocyte migration to sites of apoptosis, when secreted by apoptotic cells. Stimulates VEGFA-mediated endothelial cell migration and proliferation. Binds heparin, chondroitin sulfate and possibly other glycosaminoglycans (GAGs). Also binds specifically to pneumococcal surface protein A (PspA), the lipid A portion of bacterial lipopolysaccharide (LPS), lysozyme and DNA. Lactoferricin binds to the bacterial surface and is crucial for the bactericidal functions. Has some antiviral activity against papillomavirus infection. N-terminal region shows strong antifungal activity against C.albicans. Contains two BBXB heparin-binding consensus sequences that appear to form the predominate functional GAG-binding site. Has antimicrobial activity and is able to permeabilize different ions through liposomal membranes. Has opioid antagonist activity. Shows preference for mu-receptor. Has opioid antagonist activity. Shows higher degrees of preference for kappa-receptors than for mu-receptors. Has opioid antagonist activity. Shows higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-\|- and -Arg-Arg-Ser-Arg-\|-, and of Z-Phe-Arg-\|-aminomethylcoumarin sites. transcription factor with antiproliferative properties and ability to induce cell cycle arrest. Binds to the DeltaLf response element found in the SKP1, BAX, DCPS, and SELENOH promoters.