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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Hexokinase 2 Polyclonal Antibody

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货号 TMAB-07003

Anti-Hexokinase 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Hexokinase 2。Anti-Hexokinase 2 Polyclonal Antibody 可用于 WB。

Anti-Hexokinase 2 Polyclonal Antibody

Anti-Hexokinase 2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07003

Anti-Hexokinase 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Hexokinase 2。Anti-Hexokinase 2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Hexokinase 2 Polyclonal Antibody is a Rabbit antibody targeting Hexokinase 2. Anti-Hexokinase 2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
组织特异性Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose-6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HXK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines. HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues. Of the hexokinases, HXK III has the highest affinity for glucose. Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, determining the “set point” for insulin secretion.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Hexokinase 2
抗原种属
Human
基因名称
HK2
基因ID
3099
蛋白名称
Hexokinase-2
Uniprot ID
P52789
功能
Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
化学信息
分子量Theoretical: 101 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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