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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NAIF1 Polyclonal Antibody

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货号 TMAB-09210

Anti-NAIF1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NAIF1。Anti-NAIF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-NAIF1 Polyclonal Antibody

Anti-NAIF1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09210

Anti-NAIF1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NAIF1。Anti-NAIF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-NAIF1 Polyclonal Antibody is a Rabbit antibody targeting NAIF1. Anti-NAIF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Widely expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NAIF protein 1 (nuclear apoptosis inducing factor 1; CB12-327; RP-379C10.2) belongs to the NAIF1 family. Apoptosis is a genetically determined cell suicidal pro gram that plays critical roles in many physiological and pathological processes. nuclear apoptosis-inducing factor 1 (NAIF1), overexpression of which induces apoptosis in cells. Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. Northern blot analysis revealed wide expression of NAIF1 mRNA throughout human tissues. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NAIF1
抗原种属
Human
基因名称
NAIF1
基因ID
203245
蛋白名称
Nuclear apoptosis-inducing factor 1
Uniprot ID
Q69YI7
功能
Induces apoptosis.
化学信息
分子量Theoretical: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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