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Anti-ACTH Antibody (2I218)

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货号 TMAB-02256

Anti-ACTH Antibody (2I218) 是一种 Rabbit 抗体，靶向 ACTH。Anti-ACTH Antibody (2I218) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ACTH Antibody (2I218)

Anti-ACTH Antibody (2I218)

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Rating icon 还可以
货号 TMAB-02256

Anti-ACTH Antibody (2I218) 是一种 Rabbit 抗体，靶向 ACTH。Anti-ACTH Antibody (2I218) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-ACTH Antibody (2I218) is a Rabbit antibody targeting ACTH. Anti-ACTH Antibody (2I218) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
2I218
反应种属
Human,Rat (predicted:Mouse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性ACTH and MSH are produced by the pituitary gland.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
A synthesized peptide: human POMC
抗原种属
Human
基因名称
POMC
基因ID
5443
蛋白名称
Pro-opiomelanocortin
Uniprot ID
P01189
功能
ACTH stimulates the adrenal glands to release cortisol.
MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.
Beta-endorphin and Met-enkephalin are endogenous opiates.
化学信息
分子量Theoretical: 4.5/29 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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