Anti-YY1 Antibody (7S107)

Name: Anti-YY1 Antibody (7S107)
Brand: TargetMol
SKU: TMAH-01261
Rating: 4.5 (1 reviews)

还可以

产品编号 TMAH-01261

别名 δ transcription factor, Yin and yang 1, Transcriptional repressor protein YY1, NF-E1, INO80S, INO80 complex subunit S, Delta transcription factor

Anti-YY1 Antibody (7S107) 是一种抗体，靶向 YY1。Anti-YY1 Antibody (7S107) 可用于 ELISA。

Anti-YY1 Antibody (7S107)

还可以

产品编号 TMAH-01261 别名 δ transcription factor, Yin and yang 1, Transcriptional repressor protein YY1, NF-E1, INO80S, INO80 complex subunit S, Delta transcription factor

Anti-YY1 Antibody (7S107) 是一种抗体，靶向 YY1。Anti-YY1 Antibody (7S107) 可用于 ELISA。

规格	价格	库存	数量
50 μL	¥ 1,305	5日内发货
100 μL	¥ 2,180	5日内发货

大包装 & 定制

加入购物车

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

联系我们获取更多批次信息

资源下载

产品操作手册

产品介绍

生物活性

产品描述	Anti-YY1 Antibody (7S107) is an antibody targeting YY1. Anti-YY1 Antibody (7S107) can be used in ELISA.
别名	δ transcription factor, Yin and yang 1, Transcriptional repressor protein YY1, NF-E1, INO80S, INO80 complex subunit S, Delta transcription factor
Ig Type	Rabbit IgG
克隆号	7S107
交叉反应	Human
应用	ELISA
抗体种类	Monoclonal
亚细胞定位	Nucleus matrix. Note=Associated with the nuclear matrix.
构建方式	Recombinant Antibody
纯化方式	Affinity-chromatography
性状	Liquid
缓冲液	Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景	Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5'-CCGCCATNTT-3'; some genes have been shown to contain a longer binding motif allowing enhanced binding; the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions. May play an important role in development and differentiation. Proposed to recruit the PRC2/EED-EZH2 complex to target genes that are transcriptional repressed. Involved in DNA repair. In vitro, binds to DNA recombination intermediate structures (Holliday junctions). Plays a role in regulating enhancer activation. Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; proposed to target the INO80 complex to YY1-responsive elements.