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Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody

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Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody
产品编号 TMAC-03328
别名 p-PKC beta (Ser661), p-PKC beta (S661), PKC beta (p-Ser661), PKC beta (p-S661)

Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PKC beta (Ser661)。Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody 可用于 WB。

Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody

Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody
产品编号 TMAC-03328 别名 p-PKC beta (Ser661), p-PKC beta (S661), PKC beta (p-Ser661), PKC beta (p-S661)

Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PKC beta (Ser661)。Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC beta (Ser661). Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody can be used in WB.
别名p-PKC beta (Ser661), p-PKC beta (S661), PKC beta (p-Ser661), PKC beta (p-S661)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from HeLa cells treated with Heatshock using Phospho-PKCB (Ser661) antibody TMAC-03328. The lane on the right is treated with the antigen-specific peptide.
应用
WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 661 (G-F-S(p)-Y-T) derived from Human PKCB
抗原种属
human
Uniprot ID
P05771
化学信息
分子量Actual: 77 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pPKC beta (Ser661)pPKC beta (S661)PKC beta (pSer661)PKC beta (pS661)PKC beta (phospho-Ser661)PKC beta (phospho-S661)

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4个月前
5.0
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