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Anti-C1QBP Antibody (2O388)

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产品编号 TMAY-03169

Anti-C1QBP Antibody (2O388) 是一种 Rabbit 抗体,靶向 C1QBP。Anti-C1QBP Antibody (2O388) 可用于 ELISA。

Anti-C1QBP Antibody (2O388)

Anti-C1QBP Antibody (2O388)

Rating icon 还可以
产品编号 TMAY-03169

Anti-C1QBP Antibody (2O388) 是一种 Rabbit 抗体,靶向 C1QBP。Anti-C1QBP Antibody (2O388) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-C1QBP Antibody (2O388) is a Rabbit antibody targeting C1QBP. Anti-C1QBP Antibody (2O388) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
2O388
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse C1QBP / HABP1 (rM C1QBP / HABP1; TMPY-01998; NP_031599.2; Leu72-Gln279).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Hyaluronan binding protein 1 (HABP1), also known as p32 or gC1qR, is a ubiquitously expressed multifunctional phospho-protein implicated in cell signalling. Hyaluronan-binding protein 1 (HABP1) /p32/gC1qR was characterized as a highly acidic and oligomeric protein, which binds to different ligands like hyaluronan, C1q, and mannosylated albumin. The role of hyaluronan binding protein 1 (HABP1) in cell signaling was investigated and in vitro. HABP1 overexpressing cells showed extensive vacuolation and reduced growth rate, which was corrected by frequent medium replenishment. Further investigation revealed that HABP1 overexpressing cells undergo apoptosis, and they failed to enter into the S-phase. The sperm surface HABP1 level can be correlated with the degree of sperm motility.Hyaluronan binding protein 1 (HABP1) was reported to be present on human sperm surface and its involvement in fertilization has already been elucidated: decreased HABP1 level may be associated with low motility of sperms, which in turn might cause infertility in the patient. HABP1 also is an endogenous substrate for MAP kinase and upon mitogenic stimulation it is translocated to the nucleus in a MAP kinase-dependent manner.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse C1QBP / HABP1 protein (TMPY-01998)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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