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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Gamma Synuclein Polyclonal Antibody

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货号 TMAB-06323

Anti-Gamma Synuclein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Gamma Synuclein。Anti-Gamma Synuclein Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Gamma Synuclein Polyclonal Antibody

Anti-Gamma Synuclein Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06323

Anti-Gamma Synuclein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Gamma Synuclein。Anti-Gamma Synuclein Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Gamma Synuclein Polyclonal Antibody is a Rabbit antibody targeting Gamma Synuclein. Anti-Gamma Synuclein Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
组织特异性Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The synculein family consists of 3 highly conserved proteins of between 120 and 140 amino acids that share substantial sequence homology. Each has a series of loosely repeated motifs throughout the first 93 amino acids and an acid region toward the C terminal. The proteins are heat stable and relatively soluble. Three synucleins have been identified and termed alpha, beta and gamma synuclein and are located in the neuronal cytosol and enriched in presynaptic terminals,gamma synuclein is also expressed in many other non-neuronal tissues. Although the precise function of the synucleins are unknown a role in membrane plasticity has been suggested. The synucleins have been implicated in a number of diseases. It has been reported that in breast cancer increased expression of gamma synuclein correlates with disease progression.
抗原信息
免疫原
KLH conjugated synthetic peptide: human gamma Synuclein
抗原种属
Human
基因名称
SNCG
基因ID
6623
蛋白名称
Gamma-synuclein
Uniprot ID
O76070
功能
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
化学信息
分子量Theoretical: 13.5 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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