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Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7)

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Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7)
产品编号 TMAC-01181
别名 Tumor necrosis factor receptor superfamily member 10B, TNF-related apoptosis-inducing ligand receptor 2, Death receptor 5

Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7) 是一种 Rabbit 抗体，靶向 TRAIL R2/DR5/TNFRSF10B。Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7) 可用于 WB,IP,IHC,FCM。

Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7)

Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7)

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Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7)
产品编号 TMAC-01181 别名 Tumor necrosis factor receptor superfamily member 10B, TNF-related apoptosis-inducing ligand receptor 2, Death receptor 5

Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7) 是一种 Rabbit 抗体，靶向 TRAIL R2/DR5/TNFRSF10B。Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7) 可用于 WB,IP,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7) is a Rabbit antibody targeting TRAIL R2/DR5/TNFRSF10B. Anti-TRAIL R2/DR5/TNFRSF10B Antibody (7L7) can be used in WB,IP,IHC,FCM.
别名Tumor necrosis factor receptor superfamily member 10B, TNF-related apoptosis-inducing ligand receptor 2, Death receptor 5
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of DR5 on HL-60 cell using anti-DR5 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DR5 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-DR5 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-DR5 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-DR5 antibody. Counter stained with hematoxylin.
6. Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
应用
WB
IP
IHC
FCM
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the "death domain," that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS, DR2 (or TRUNDD), DR3 (Death Receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O14763
化学信息
分子量Theoretical: 48 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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