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Anti-P Glycoprotein Antibody (1U603)

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货号 TMAB-01311

别名 PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20

Anti-P Glycoprotein Antibody (1U603) 是一种 Rabbit 抗体,靶向 P Glycoprotein。Anti-P Glycoprotein Antibody (1U603) 可用于 IF, IHC-Fr, IHC-P, WB。

Anti-P Glycoprotein Antibody (1U603)

Anti-P Glycoprotein Antibody (1U603)

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Rating icon 还可以
货号 TMAB-01311 别名 PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20

Anti-P Glycoprotein Antibody (1U603) 是一种 Rabbit 抗体,靶向 P Glycoprotein。Anti-P Glycoprotein Antibody (1U603) 可用于 IF, IHC-Fr, IHC-P, WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-P Glycoprotein Antibody (1U603) is a Rabbit antibody targeting P Glycoprotein. Anti-P Glycoprotein Antibody (1U603) can be used in IF, IHC-Fr, IHC-P, WB.
别名PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20
Ig Type
IgG
克隆号
1U603
反应种属
Human,Mouse,Rat
验证活性
1. Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Mouse Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
7. Paraformaldehyde-fixed, paraffin embedded Rat Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
8. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
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应用IFIHC-FrIHC-PWB
推荐剂量
IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Expressed in liver, kidney, small intestine and brain.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
浓度1 mg/mL
研究背景P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.
抗原信息
免疫原
Recombinant Protein: Human P-glycoprotein 1 protein
抗原种属
Human
基因名称
ABCB1
基因ID
蛋白名称
ATP-dependent translocase ABCB1
Uniprot ID
研究领域
P glycoproteins,ATPases,Channels,Side Population,Surface Molecules
功能
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Subunit : Interacts with PSMB5.
化学信息
分子量Theoretical: 141 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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