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Anti-Fetuin A Antibody (9Y147)
还可以产品编号 TMAY-03100
Anti-Fetuin A Antibody (9Y147) 是一种 Rabbit 抗体，靶向 Fetuin A。Anti-Fetuin A Antibody (9Y147) 可用于 IHC-P。
Anti-Fetuin A Antibody (9Y147)
Anti-Fetuin A Antibody (9Y147)
还可以产品编号 TMAY-03100
Anti-Fetuin A Antibody (9Y147) 是一种 Rabbit 抗体，靶向 Fetuin A。Anti-Fetuin A Antibody (9Y147) 可用于 IHC-P。
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偶联与修饰
抗原信息
| 产品描述 | Anti-Fetuin A Antibody (9Y147) is a Rabbit antibody targeting Fetuin A. Anti-Fetuin A Antibody (9Y147) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9Y147 |
| 交叉反应 | Mouse |
| 验证活性 | Immunochemical staining of mouse AHSG in mouse liver (from 2 donors) with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Fetuin-A / AHSG (rM Fetuin-A / AHSG; TMPY-00802; NP_038493.1; Met1-Ile345). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Fetuin-A, also known as Alpha-2-HS-Glycoprotein (AHSG), belongs to the Fetuin family, is a plasma binding protein, and is more abundant in fetal than adult blood. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Fetuins are carrier proteins like albumin. Fetuin-A forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus Fetuin-A is a potent inhibitor of pathological calcification. The circulating levels of fetuin-A, a well-described inhibitor of calcification, regulate the cell-dependent process of osteogenesis. The low circulating fetuin-A levels are associated with a greater prevalence and/or severity of Vascular calcification (VC) and increased risk for all-cause and cardiovascular mortality. However, high circulating fetuin-A levels appear to induce insulin resistance and, in non-dialyzed subjects with diabetic nephropathy, are directly related to VC burden. The emerging role of fetuin-A deficiency as a risk factor in dialysis patients was documented in cross-sectional studies demonstrating a significant correlation with all-cause and cardiovascular mortality. Additionally, Human fetuin-A is a negative acute phase protein involved in inflammatory diseases, thus being a potential physiological regulator of meprin activity. Fetuin-A is a broad-range protease inhibitor. Fetuin-A and cystatin C as endogenous proteolytic regulators of meprin activity broadens our understanding of the proteolytic network in plasma. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse Fetuin-A / AHSG protein (TMPY-00802) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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