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Anti-MMP-3 Antibody (9W229)
还可以产品编号 TMAY-00865
Anti-MMP-3 Antibody (9W229) 是一种 Mouse 抗体，靶向 MMP-3。Anti-MMP-3 Antibody (9W229) 可用于 ELISA(Cap)。
Anti-MMP-3 Antibody (9W229)
Anti-MMP-3 Antibody (9W229)
还可以产品编号 TMAY-00865
Anti-MMP-3 Antibody (9W229) 是一种 Mouse 抗体，靶向 MMP-3。Anti-MMP-3 Antibody (9W229) 可用于 ELISA(Cap)。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-MMP-3 Antibody (9W229) is a Mouse antibody targeting MMP-3. Anti-MMP-3 Antibody (9W229) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9W229 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MMP-3 (rh MMP-3; TMPY-02689; AAA36321.1; Tyr18-Thr272). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human MMP-3 Protein (TMPY-02689) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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