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Anti-MACF1/ACF7 Polyclonal Antibody

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货号 TMAB-08491

Anti-MACF1/ACF7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MACF1/ACF7。Anti-MACF1/ACF7 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MACF1/ACF7 Polyclonal Antibody

Anti-MACF1/ACF7 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08491

Anti-MACF1/ACF7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MACF1/ACF7。Anti-MACF1/ACF7 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-MACF1/ACF7 Polyclonal Antibody is a Rabbit antibody targeting MACF1/ACF7. Anti-MACF1/ACF7 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic, microtubule. Plasma membrane. Golgi apparatus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Microtubule-actin crosslinking factor 1 (MACF1/ACF7) belongs to spectraplakin family of proteins which also includes mammalian Bpag1/dystonin, Drosophila Short Stop (Shot) and Caenorhabditis elegans Vab-10. These are large actin-microtubule linker molecules that are essential for various biological processes such as neuronal degeneration, wound healing, gastrulation. MACF1, located on mouse chromosome 4D2.2, was found to play an important role during neurogenesis- it was shown that MACF1 regulates the organization of neuronal microtubules which is essential for axon extension. Furthermore, MACF1 is required in controlling focal adhesion assembly and dynamics. MACF1 behaves as an actin-regulated ATPase and it has the ability to target microtubules that track along F-actin to focal adhesions. MACF1 was also implicated in regulating filopodia formation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MACF1/ACF7
抗原种属
Human
基因名称
Macf1
基因ID
23499
蛋白名称
Microtubule-actin cross-linking factor 1
化学信息
分子量Theoretical: 839 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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