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Anti-SOX-2 Antibody (1T706) 是一种抗体,靶向 SOX-2。Anti-SOX-2 Antibody (1T706) 可用于 ELISA, WB, IHC。
Anti-SOX-2 Antibody (1T706) 是一种抗体,靶向 SOX-2。Anti-SOX-2 Antibody (1T706) 可用于 ELISA, WB, IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,310 | 5日内发货 | |
100 μL | ¥ 2,185 | 5日内发货 |
产品描述 | Anti-SOX-2 Antibody (1T706) is an antibody targeting SOX-2. Anti-SOX-2 Antibody (1T706) can be used in ELISA, WB, IHC. |
Ig Type | Rabbit IgG |
克隆号 | 1T706 |
交叉反应 | Human, Mouse, Rat |
验证活性 | 1. Western Blot -Positive WB detected in: U-251 whole cell lysate, MCF-7 whole cell lysate, Mouse Brain whole cell lysate, Rat Brain whole cell lysate -All lanes: SOX2 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 35 kDa -Observed band size: 40 kDa 2. IHC image of TMAH-01126 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
应用 | ELISA, WB, IHC |
推荐剂量 | WB:1:500-1:5000; IHC:1:50-1:200. |
抗体种类 | Monoclonal |
亚细胞定位 | Nucleus. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell pluripotency. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. May function as a switch in neuronal development. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human SOX2 |
抗原种属 | Human |
基因ID | 6657 |
Uniprot ID | |
研究领域 | Epigenetics and Nuclear Signaling, Neuroscience, Developmental biology, Signal transduction, Stem cells |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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