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Anti-IL-18BP Antibody (4K247)
还可以产品编号 TMAY-00683
Anti-IL-18BP Antibody (4K247) 是一种 Rabbit 抗体，靶向 IL-18BP。Anti-IL-18BP Antibody (4K247) 可用于 ELISA。
Anti-IL-18BP Antibody (4K247)
Anti-IL-18BP Antibody (4K247)
还可以产品编号 TMAY-00683
Anti-IL-18BP Antibody (4K247) 是一种 Rabbit 抗体，靶向 IL-18BP。Anti-IL-18BP Antibody (4K247) 可用于 ELISA。
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-18BP Antibody (4K247) is a Rabbit antibody targeting IL-18BP. Anti-IL-18BP Antibody (4K247) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4K247 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL18BP / IL18BPa (rh IL18BP / IL18BPa ; TMPY-00846; NP_001034748.1; Met1-Gly194). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. The adjacently located family members IL18 Receptor 1 (IL18R1) and IL18 receptor accessory protein (IL18RAP) may also be important in the development of asthma and atopy. IL-18 binding protein (IL-18BP) was only moderately elevated, resulting in a high level of biologically active free IL-18 in HPS. A severe IL-18/IL-18BP imbalance results in Th-1 lymphocyte and macrophage activation, which escapes control by NK-cell cytotoxicity and may allow for secondary HPS in patients with underlying diseases. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL18BP / IL18BPa protein (TMPY-00846) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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