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Anti-CD40 Antibody (2Z619) 是一种 Rabbit 抗体,靶向 CD40。Anti-CD40 Antibody (2Z619) 可用于 WB。
Anti-CD40 Antibody (2Z619) 是一种 Rabbit 抗体,靶向 CD40。Anti-CD40 Antibody (2Z619) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-CD40 Antibody (2Z619) is a Rabbit antibody targeting CD40. Anti-CD40 Antibody (2Z619) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 2Z619 |
| 反应种属 | Human |
| 验证活性 | 1. 25 μg total protein per lane of various lysates (see on figure) probed with CD40 monoclonal antibody, unconjugated (TMAB-03983) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. 2. 25 μg total protein per lane of various lysates (see on figure) probed with CD40 monoclonal antibody, unconjugated (TMAB-03983) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted. |
| 组织特异性 | B-cells and in primary carcinomas. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | PBS, Glycerol, BSA. |
| 浓度 | 1mg/ml |
| 研究背景 | Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022] |
| 免疫原 | KLH conjugated synthetic peptide: human CD40 |
| 抗原种属 | Human |
| 基因名称 | Cd40 |
| 基因ID | |
| 蛋白名称 | Tumor necrosis factor receptor superfamily member 5 |
| Uniprot ID |
| 分子量 | Theoretical: 30 kDa. Actual: 44-50 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |