购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HDAC10 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06926

Anti-HDAC10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HDAC10。Anti-HDAC10 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HDAC10 Polyclonal Antibody

Anti-HDAC10 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06926

Anti-HDAC10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HDAC10。Anti-HDAC10 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-HDAC10 Polyclonal Antibody is a Rabbit antibody targeting HDAC10. Anti-HDAC10 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Excluded from the nucleoli.
组织特异性Ubiquitous. High expression in liver, spleen, pancreas and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The enzymes responsible for the reversible acetylation/ deacetylation process of histones are histone acetyltransferases (HATs) and histone deacetylases (HDACs), respectively. HATs act as transcriptional coactivators and HDACs are part of transcriptional corepressor complexes. Mammalian HDACs can be divided into three classes according to sequence homology. Class I consists of the yeast Rpd3 like proteins HDAC1, HDAC2, HDAC3, and HDAC8. Class II consists of the yeast Hda1 like proteins HDAC10, HDAC5, HDAC6, HDAC7, HDAC9, and HDAC10. Class III comprises the yeast Sir2 like proteins. Whereas class I HDACs are ubiquitously expressed, most class II HDACs are tissue specific. HDAC10 is similar to HDAC6, both containing a unique putative second catalytic domain not found in other HDACs. However, this domain is not functional in HDAC10. The deacetylase activity of class II HDACs is regulated by subcellular localization. HDAC10 was localized to both the nucleus and cytoplasm. HDAC10 can deacetylate histones, repress transcription, and interact with HDAC3.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HDAC10
抗原种属
Human
基因名称
HDAC10
基因ID
83933
蛋白名称
Polyamine deacetylase HDAC10
Uniprot ID
Q969S8
功能
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-HDAC10 Polyclonal Antibody | purchase Anti-HDAC10 Polyclonal Antibody | Anti-HDAC10 Polyclonal Antibody cost | order Anti-HDAC10 Polyclonal Antibody | Anti-HDAC10 Polyclonal Antibody molecular weight