Anti-SCF Antibody (8A235)

Name: Anti-SCF Antibody (8A235)
Brand: TargetMol
SKU: TMAY-00846
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00846

Anti-SCF Antibody (8A235) 是一种 Mouse 抗体，靶向 SCF。Anti-SCF Antibody (8A235) 可用于 ELISA。

Anti-SCF Antibody (8A235)

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产品编号 TMAY-00846

Anti-SCF Antibody (8A235) 是一种 Mouse 抗体，靶向 SCF。Anti-SCF Antibody (8A235) 可用于 ELISA。

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产品描述	Anti-SCF Antibody (8A235) is a Mouse antibody targeting SCF. Anti-SCF Antibody (8A235) can be used in ELISA.
Ig Type	Monoclonal Mouse IgG1
克隆号	8A235
交叉反应	Human
应用	ELISA
推荐剂量	ELISA: 1:1000-1:2000
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KITLG/SCF/C-kit ligand (rh KITLG/SCF/C-kit ligand; TMPY-02170; P21583-1; Met1-Ala189). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. SCF/C-kit ligand stimulates the proliferation of mast cells. This protein can augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It may act synergistically with other cytokines, probably interleukins SCF/C-kit ligand is the ligand for the tyrosine kinase receptor c-kit, which is expressed on both primitive and mature hematopoietic progenitor cells. In vitro, SCF/C-kit ligand synergizes with other growth factors, such as granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor, and interleukin-3 to stimulate the proliferation and differentiation of cells of the lymphoid, myeloid, erythroid, and megakaryocytic lineages. In vivo, SCF/C-kit also synergizes with other growth factors and has been shown to enhance the mobilization of peripheral blood progenitor cells in combination with G-CSF. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human KITLG/SCF/C-kit ligand Protein (TMPY-02170)
抗原种属	Human
研究领域	Cardiac Stem Cell Markers

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.