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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IL-1 beta Polyclonal Antibody

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货号 TMAB-00932

Anti-IL-1 beta Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-1 beta。Anti-IL-1 beta Polyclonal Antibody 可用于 WB。

Anti-IL-1 beta Polyclonal Antibody

Anti-IL-1 beta Polyclonal Antibody

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货号 TMAB-00932

Anti-IL-1 beta Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-1 beta。Anti-IL-1 beta Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-1 beta Polyclonal Antibody is a Rabbit antibody targeting IL-1 beta. Anti-IL-1 beta Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Human
验证活性
Sample:
Lane 1: Normal Mouse Raw264.7 cell lysates
Lane 2: Raw264.7 treated with 100ng/ml lipopolysaccharide (LPS) for 6h, then with 300ng/ml Brefeldin A added after 3 hours
Primary: Anti-IL-1 Beta (TMAB-00932) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17/32 kDa
Observed band size: 35 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human IL-1beta
抗原种属
Human
基因名称
IL1B
基因ID
3553
蛋白名称
Interleukin-1 beta
Uniprot ID
P01584
研究领域
Inflammatory mediators,Interleukins,Obesity,SARS Coronavirus
功能
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
化学信息
分子量Theoretical: 17/32 kDa. Actual: 17/32 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

Interleukin-1Interleukin1il1b
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