Name: REG3B Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-03673
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 582

6-8日内发货

10 μg

¥ 939

6-8日内发货

20 μg

¥ 1,590

5日内发货

50 μg

¥ 3,670

5日内发货

生物活性

产品描述	Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its expression level in colorectal tumors correlated inversely with pSTAT3 level and survival times of patients. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells. This pathway might be targeted in patients with colitis to reduce carcinogenesis.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its expression level in colorectal tumors correlated inversely with pSTAT3 level and survival times of patients. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells. This pathway might be targeted in patients with colitis to reduce carcinogenesis.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	P35230
蛋白构建	A DNA sequence encoding the mouse REG3B (NP_035166.1) (Met1-Gly175) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Glu 27
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	REG-III, PAP1, Pap, HIP
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	49.2 kDa (predicted); 19 kDa (reducing condition, due to glycosylation)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

REG3B Protein, Mouse, Recombinant (His)

REG3B Protein, Mouse, Recombinant (His)

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