购物车

您的购物车当前为空

MINA53 inhibitor (Compound 10)

Name: MINA53 inhibitor (Compound 10)
Brand: TargetMol
SKU: T35398
Price: 280 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.64%

货号 T35398

MINA53 inhibitor 是 MINA53 的抑制剂。

为众多的药物研发团队赋能，

让新药发现更简单！

MINA53 inhibitor (Compound 10)

一键复制产品信息

很棒

纯度: 99.64%

货号 T35398

MINA53 inhibitor 是 MINA53 的抑制剂。

规格	价格	库存
1 mg	¥ 280	现货
2 mg	¥ 397	现货
5 mg	¥ 678	现货
10 mg	¥ 1,060	现货
25 mg	¥ 1,980	现货
50 mg	¥ 2,950	现货
100 mg	¥ 3,970	现货
200 mg	¥ 5,520	现货
1 mL x 10 mM (in DMSO)	¥ 592	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.64%

颜色: 白色

性状: Solid

联系我们获取更多批次信息

资源下载:

COA LCMS 产品操作手册

产品介绍

MINA53 inhibitor (Compound 10) AI Summary

MINA53 inhibitor (Compound 10) demonstrates a diverse range of bioactivities, including synergistic cytotoxicity against human U-87MG cells with doxorubicin, evidenced by low combination index values (CI = 0.21, 0.13, 0.18) and a 75.0% reduction in cell viability at 20 µM. It inhibits human FIH with an in vitro IC50 of 29800.0 nM, recombinant human NO66 with an IC50 of 36900.0 nM, and recombinant human MINA53 with an IC50 of 1500.0 nM. Additionally, it inhibits various histone demethylases (KDM2A, KDM3B, KDM4A, KDM4D, KDM5B, KDM6B) with IC50 values ranging from 57500.0 nM to 74200.0 nM. The compound also exhibits antiproliferative activity against human NB-4 (IC50 = 94000.0 nM) and HL-60 (IC50 = 14000.0 nM) cells, and induces apoptosis in human U87-MG cells with a 60.0% activity level. These findings suggest that MINA53 inhibitor (Compound 10) has significant potential in cytotoxicity, antiproliferative effects, apoptosis induction, and inhibition of enzymes involved in histone demethylation..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	MINA53 inhibitor (Compound 10) is an inhibitor of MINA53.

化学信息

分子量	290.34
分子式	C₁₄H₁₄N₂O₃S
Smiles	O=C(C1=CN=C(SCCCC2=CC=CC=C2)NC1=O)O

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

Ethanol: 3 mg/mL (10.33 mM), Sonication is recommended.

DMSO: 55 mg/mL (189.43 mM), Sonication is recommended.

溶液配制表

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4442 mL	17.2212 mL	34.4424 mL	172.2119 mL
5 mM	0.6888 mL	3.4442 mL	6.8885 mL	34.4424 mL
10 mM	0.3444 mL	1.7221 mL	3.4442 mL	17.2212 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1722 mL	0.8611 mL	1.7221 mL	8.6106 mL
50 mM	0.0689 mL	0.3444 mL	0.6888 mL	3.4442 mL
100 mM	0.0344 mL	0.1722 mL	0.3444 mL	1.7221 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

MINA-53 inhibitor (Compound 10)MINA53 inhibitor (Compound 10)MINA53 inhibitor MINA53 Compound 10

Related Tags: buy MINA53 inhibitor (Compound 10) | purchase MINA53 inhibitor (Compound 10) | MINA53 inhibitor (Compound 10) cost | order MINA53 inhibitor (Compound 10) | MINA53 inhibitor (Compound 10) chemical structure | MINA53 inhibitor (Compound 10) formula | MINA53 inhibitor (Compound 10) molecular weight

MINA53 inhibitor (Compound 10)

MINA53 inhibitor (Compound 10)