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Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Cortactin (Thr466)。Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody 可用于 WB。
Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Cortactin (Thr466)。Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Thr466). Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010] |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human Cortactin around the phosphorylation site of Thr466 |
| 抗原种属 | Human |
| 基因名称 | CTTN |
| 基因ID | |
| 蛋白名称 | Src substrate cortactin |
| Uniprot ID | |
| 功能 | Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases. |
| 分子量 | Theoretical: 61 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |