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顶部生物活性储存和溶解信息计算器

Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2

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产品编号 TMAB-10729

Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-GATA2 (Ser401)。Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2 可用于 WB。

Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2

Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10729

Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-GATA2 (Ser401)。Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GATA2 (Ser401). Anti-Phospho-GATA2 (Ser401) Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
交叉反应
Human (predicted:Pig,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Endothelial cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human GATA2 around the phosphorylation site of Ser401
抗原种属
Human
基因名称
GATA2
基因ID
2624
蛋白名称
Endothelial transcription factor GATA-2
Uniprot ID
P23769
功能
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
化学信息
分子量Theoretical: 53 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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