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Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MAPK14 (Thr180)。Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody 可用于 WB,IHC。
Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MAPK14 (Thr180)。Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Thr180). Anti-Phospho-MAPK14 (Thr180) Polyclonal Antibody can be used in WB,IHC. |
别名 | p-MAPK14 (Thr180), p-MAPK14 (T180), MAPK14 (p-Thr180), MAPK14 (p-T180) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from HT29 cells untreated or treated with UV using P38 MAPK (Phospho-Thr180) Antibody TMAC-02957. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using P38 MAPK (Phospho-Thr180) Antibody TMAC-02957 (left) or the same antibody preincubated with blocking peptide (right). 3. Western blot analysis of extracts from HL60 cells, treated with TNFa or calf intestinal phosphatase (CIP), using P38 MAPK (Phospho-Thr180) Antibody TMAC-02957. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of threonine 180 (E-M-T(p)-G-Y ) derived from Human P38MAPK |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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