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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KIF7 Polyclonal Antibody

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货号 TMAB-08057

Anti-KIF7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KIF7。Anti-KIF7 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-KIF7 Polyclonal Antibody

Anti-KIF7 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08057

Anti-KIF7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KIF7。Anti-KIF7 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-KIF7 Polyclonal Antibody is a Rabbit antibody targeting KIF7. Anti-KIF7 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell projection; cilium. SMO is required for its accumulation within cilia. Moves from the cilia base to the cilia tip in response to activation of the Shh pathway.
组织特异性Embryonic stem cells, melanotic melanoma and Jurkat T-cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景KIF7 is a 1,343 amino acid protein expressed in embryonic stem cells, melanotic melanoma and Jurkat T-cells. KIF7 is a member of the KIF27 subfamily of the kinesin-like protein family and contains one kinesin-motor domain. It is suggested that KIF7 may participate in the Hedgehog (Hh) signaling pathway by regulating the proteolysis and stability of GLI transcription factors. Hedgehog (Hh) signaling plays a critical role in embryonic development.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KIF7
抗原种属
Human
基因名称
KIF7
基因ID
374654
蛋白名称
Kinesin-like protein KIF7
Uniprot ID
Q2M1P5
功能
Acts as both a negative and positive regulator of sonic hedgehog (Shh) pathway, acting downstream of SMO. Negatively regulates the pathway by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand. Positively regulates the pathway by preventing the processing of the transcription factor GLI3 into its repressor form. Required for efficient localization of GLI3 to cilia in response to Shh. May also act as a ciliary motor.
化学信息
分子量Theoretical: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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