Name: CD31/PECAM-1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-00970
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 273

3日内发货

10 μg

¥ 429

3日内发货

20 μg

¥ 695

3日内发货

50 μg

¥ 1,350

3日内发货

100 μg

¥ 2,260

现货

200 μg

¥ 4,430

5日内发货

500 μg

¥ 10,770

5日内发货

生物活性

产品描述	CD31/PECAM-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66 kDa and the accession number is EAW94208.1.
生物活性	Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When 8×104 cells/well are added to CD31-His coated plates (5 μg/mL, 100 μL/well) in the presence of 10 μg/mL PHA, approximately >70% will adhere after 30 minutes at 37℃.
研究背景	The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	EAW94208.1
蛋白构建	A DNA sequence encoding the extracellular domain (Met 1-Lys 601) of human CD31 (EAW94208.1) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Gln 28
蛋白纯度	> 97 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	platelet/endothelial cell adhesion molecule 1, PECAM-1, PECA1, GPIIA', endoCAM, CD31/EndoCAM, CD31
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	66 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)
颜色	White
物理性状	Lyophilized powder

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CD31/PECAM-1 Protein, Human, Recombinant (His)

CD31/PECAM-1 Protein, Human, Recombinant (His)

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