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Anti-DEPTOR Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 DEPTOR。Anti-DEPTOR Polyclonal Antibody 3 可用于 WB。
Anti-DEPTOR Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 DEPTOR。Anti-DEPTOR Polyclonal Antibody 3 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-DEPTOR Polyclonal Antibody 3 is a Rabbit antibody targeting DEPTOR. Anti-DEPTOR Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8. |
| 免疫原 | KLH conjugated synthetic peptide: human DEPTOR |
| 抗原种属 | Human |
| 基因名称 | DEPTOR |
| 基因ID | |
| 蛋白名称 | DEP domain-containing mTOR-interacting protein |
| Uniprot ID | |
| 功能 | Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. |
| 分子量 | Theoretical: 46 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |