Anti-H1N1 Matrix Protein 1 Polyclonal Antibody is a Rabbit antibody targeting H1N1 Matrix Protein 1. Anti-H1N1 Matrix Protein 1 Polyclonal Antibody can be used in WB.

IgG

Influenza A virus H1N1

20 ng Influenza A virus H1N1 Nucleoprotein, C-His per Lane probed with H1N1 Matrix Protein 1 polyclonal antibody respectively, unconjugated (TMAB-00824) at 1:1000 dilution and 4°C overnight incubation. Followed by corresponding conjugated secondary antibody incubation at RT for 60 min.

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: H1N1 Matrix Protein 1

NP

Nucleoprotein

Influenza,Viral Protein

Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.