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顶部生物活性储存和溶解信息计算器

Anti-METAP2 Antibody (2D279)

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Anti-METAP2 Antibody (2D279)
产品编号 TMAC-02574
别名 p67eIF2, p67, MNPEP, methionyl aminopeptidase 2, MAP2

Anti-METAP2 Antibody (2D279) 是一种 Rabbit 抗体，靶向 METAP2。Anti-METAP2 Antibody (2D279) 可用于 WB,ICC,IF,IHC,FCM。

Anti-METAP2 Antibody (2D279)

Anti-METAP2 Antibody (2D279)

Rating icon 还可以
Anti-METAP2 Antibody (2D279)
产品编号 TMAC-02574 别名 p67eIF2, p67, MNPEP, methionyl aminopeptidase 2, MAP2

Anti-METAP2 Antibody (2D279) 是一种 Rabbit 抗体，靶向 METAP2。Anti-METAP2 Antibody (2D279) 可用于 WB,ICC,IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-METAP2 Antibody (2D279) is a Rabbit antibody targeting METAP2. Anti-METAP2 Antibody (2D279) can be used in WB,ICC,IF,IHC,FCM.
别名p67eIF2, p67, MNPEP, methionyl aminopeptidase 2, MAP2
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Methionine Aminopeptidase 2 on Hela cell using anti-Methionine Aminopeptidase 2 antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi, Lane 2: K562, Lane 3: Mouse thymus, Lane 4: Mouse kidney.
2. Immunohistochemical analysis of paraffin-embedded rat seminal vesicle tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
7. ICC staining Methionine Aminopeptidase 2 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining Methionine Aminopeptidase 2 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining Methionine Aminopeptidase 2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. Flow cytometric analysis of Daudi cells with Methionine Aminopeptidase 2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
WB
ICC
IF
IHC
FCM
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC:IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: within C-terminal human Methionine Aminopeptidase 2
抗原种属
human
Uniprot ID
P50579
化学信息
分子量Theoretical: 53 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

MAP-2MAP 2

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