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Anti-METAP2 Antibody (2D279)

Synonyms: p67eIF2, p67, MNPEP, methionyl aminopeptidase 2, MAP2
货号 TMAC-02574 一键复制产品信息
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Anti-METAP2 Antibody (2D279) 是一种 Rabbit 抗体,靶向 METAP2。Anti-METAP2 Antibody (2D279) 可用于 FCM,ICC,IF,IHC,WB。

Anti-METAP2 Antibody (2D279)

一键复制产品信息
Rating icon 还可以
202603开学季活动
货号 TMAC-02574

别名 p67eIF2, p67, MNPEP, methionyl aminopeptidase 2, MAP2

Anti-METAP2 Antibody (2D279) 是一种 Rabbit 抗体,靶向 METAP2。Anti-METAP2 Antibody (2D279) 可用于 FCM,ICC,IF,IHC,WB。

Anti-METAP2 Antibody (2D279)
规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
库存状态实时更新,以官网显示为准,现货产品可直接加购物车下单
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产品介绍


生物活性
产品描述
Anti-METAP2 Antibody (2D279) is a Rabbit antibody targeting METAP2. Anti-METAP2 Antibody (2D279) can be used in FCM,ICC,IF,IHC,WB.
别名
p67eIF2, p67, MNPEP, methionyl aminopeptidase 2, MAP2
Ig Type
IgG
克隆号
2D279
反应种属
Human,Mouse,Rat
验证活性
1. Western blot analysis of Methionine Aminopeptidase 2 on Hela cell using anti-Methionine Aminopeptidase 2 antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi, Lane 2: K562, Lane 3: Mouse thymus, Lane 4: Mouse kidney.
2. Immunohistochemical analysis of paraffin-embedded rat seminal vesicle tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Methionine Aminopeptidase 2 antibody. Counter stained with hematoxylin.
7. ICC staining Methionine Aminopeptidase 2 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining Methionine Aminopeptidase 2 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining Methionine Aminopeptidase 2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. Flow cytometric analysis of Daudi cells with Methionine Aminopeptidase 2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
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应用FCMICCIFIHCWB
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC:IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: within C-terminal human Methionine Aminopeptidase 2
抗原种属
Human
Uniprot ID
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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