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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-P4HB Antibody (9C640)

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货号 TMAB-09876

Anti-P4HB Antibody (9C640) 是一种 Rabbit 抗体，靶向 P4HB。Anti-P4HB Antibody (9C640) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-P4HB Antibody (9C640)

Anti-P4HB Antibody (9C640)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09876

Anti-P4HB Antibody (9C640) 是一种 Rabbit 抗体，靶向 P4HB。Anti-P4HB Antibody (9C640) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-P4HB Antibody (9C640) is a Rabbit antibody targeting P4HB. Anti-P4HB Antibody (9C640) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
9C640
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum lumen. Melanosome. Cell membrane; Peripheral membrane protein (Potential). Note=Highly abundant. In some cell types, seems to be also secreted or associated with the plasma membrane, where it undergoes constant shedding and replacement from intracellular sources (Probable). Localizes near CD4-enriched regions on lymphoid cell surfaces. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
组织特异性Detected in the flagellum and head region of spermatozoa (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell.
抗原信息
免疫原
A synthesized peptide: human PDI
抗原种属
Human
基因名称
P4HB
基因ID
5034
蛋白名称
Protein disulfide-isomerase
Uniprot ID
P07237
功能
This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.
化学信息
分子量Theoretical: 57 kDa. Actual: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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