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Anti-CLASP1 Antibody (1L48)

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货号 TMAB-04414

Anti-CLASP1 Antibody (1L48) 是一种 Rabbit 抗体,靶向 CLASP1。Anti-CLASP1 Antibody (1L48) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-CLASP1 Antibody (1L48)

Anti-CLASP1 Antibody (1L48)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04414

Anti-CLASP1 Antibody (1L48) 是一种 Rabbit 抗体,靶向 CLASP1。Anti-CLASP1 Antibody (1L48) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-CLASP1 Antibody (1L48) is a Rabbit antibody targeting CLASP1. Anti-CLASP1 Antibody (1L48) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
1L48
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cytoplasm,cytoskeleton, centrosome. Chromosome, centromere, kinetochore.Cytoplasm, cytoskeleton, spindle. Golgi apparatus, trans-Golginetwork (Probable). Note=Localizes to microtubule plus ends.Localizes to centrosomes, kinetochores and the mitotic spindle fromprometaphase. Subsequently localizes to the spindle midzone fromanaphase and to the midbody from telophase. In migrating cellslocalizes to the plus ends of microtubules within the cell body andto the entire microtubule lattice within the lamella. Localizes tothe cell cortex and this requires ERC1 and PHLDB2
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2.
抗原信息
免疫原
A synthesized peptide: human CLASP1
抗原种属
Human
基因名称
CLASP1
基因ID
蛋白名称
CLIP-associating protein 1
Uniprot ID
功能
Microtubule plus-end tracking protein that promotes thestabilization of dynamic microtubules. Involved in the nucleationof noncentrosomal microtubules originating from the trans-Golginetwork (TGN). Required for the polarization of the cytoplasmicmicrotubule arrays in migrating cells towards the leading edge ofthe cell. May act at the cell cortex to enhance the frequency ofrescue of depolymerizing microtubules by attaching their plus-endsto cortical platforms composed of ERC1 and PHLDB2. This corticalmicrotubule stabilizing activity is regulated at least in part byphosphatidylinositol 3-kinase signaling. Also performs a similarstabilizing function at the kinetochore which is essential for thebipolar alignment of chromosomes on the mitotic spindle.
化学信息
分子量Theoretical: 169 kDa. Actual: 169 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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