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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Ferritin Heavy Chain Polyclonal Antibody

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货号 TMAB-05965

Anti-Ferritin Heavy Chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ferritin Heavy Chain。Anti-Ferritin Heavy Chain Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Ferritin Heavy Chain Polyclonal Antibody

Anti-Ferritin Heavy Chain Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05965

Anti-Ferritin Heavy Chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ferritin Heavy Chain。Anti-Ferritin Heavy Chain Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Ferritin Heavy Chain Polyclonal Antibody is a Rabbit antibody targeting Ferritin Heavy Chain. Anti-Ferritin Heavy Chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic.
组织特异性In human liver the heavy chain is the major chain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Mammalian ferritins consist of 24 subunits made up of two types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of FeII, whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of FeIII. The most prominent role of mamma-lian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed; and oxidative stress, an important factor in the development of aging-related cataracts.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Ferritin Heavy Chain
抗原种属
Human
基因名称
FTH1
基因ID
2495
蛋白名称
Ferritin heavy chain
Uniprot ID
P02794
功能
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
化学信息
分子量Theoretical: 21 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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