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Anti-Chymase 1 Antibody (7I538)
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产品编号 TMAC-02479
别名 Mcpt5, Mast cell protease I, Mast cell protease 5 (mMCP-5), Mast cell chymase 1, Cma1, Chymase, Alpha-chymase
Anti-Chymase 1 Antibody (7I538) 是一种 Rabbit 抗体，靶向 Chymase 1。Anti-Chymase 1 Antibody (7I538) 可用于 WB,IHC。
Anti-Chymase 1 Antibody (7I538)
Anti-Chymase 1 Antibody (7I538)
还可以产品编号 TMAC-02479 别名 Mcpt5, Mast cell protease I, Mast cell protease 5 (mMCP-5), Mast cell chymase 1, Cma1, Chymase, Alpha-chymase
Anti-Chymase 1 Antibody (7I538) 是一种 Rabbit 抗体，靶向 Chymase 1。Anti-Chymase 1 Antibody (7I538) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-Chymase 1 Antibody (7I538) is a Rabbit antibody targeting Chymase 1. Anti-Chymase 1 Antibody (7I538) can be used in WB,IHC. |
| 别名 | Mcpt5, Mast cell protease I, Mast cell protease 5 (mMCP-5), Mast cell chymase 1, Cma1, Chymase, Alpha-chymase |
| Ig Type | IgG |
| 克隆号 | 7I538 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of Mast Cell Chymase on rat spleen and mouse spleen tissue lysates using anti-Mast Cell Chymase antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-Mast Cell Chymase antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Mast Cell Chymase antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast Cell Chymase, also known as CMA1 or MCT1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19 amino acid signal peptide, an acidic 2 amino acid propeptide and a 226 amino acid catalytic domain. Mast Cell Chymase is a chymotryptic serine proteinase which is a member of the peptidase family S1. Expressed in mast cells, Mast Cell Chymase is associated with the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function. Mast Cell Protease 1, also designated Mcp-1 or Mcpt1, is a rodent specific beta-chymase. The mouse and rat Mast Cell Protease 1 proteins share 76% sequence identity at the amino acid level. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 27 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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