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Anti-AIF1 Antibody (9M864)

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货号 TMAB-02394

Anti-AIF1 Antibody (9M864) 是一种 Rabbit 抗体，靶向 AIF1。Anti-AIF1 Antibody (9M864) 可用于 WB。

Anti-AIF1 Antibody (9M864)
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Anti-AIF1 Antibody (9M864)

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Rating icon 还可以
货号 TMAB-02394

Anti-AIF1 Antibody (9M864) 是一种 Rabbit 抗体，靶向 AIF1。Anti-AIF1 Antibody (9M864) 可用于 WB。

规格价格库存数量
200 μg
¥ 5,595
5日内发货
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
200 μL
¥ 3,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-AIF1 Antibody (9M864) is a Rabbit antibody targeting AIF1. Anti-AIF1 Antibody (9M864) can be used in WB.
Ig Type
IgG
克隆号
9M864
反应种属
Mouse
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
组织特异性Detected in T-lymphocytes and peripheral blood mononuclear cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with chronic inflammatory processes. AIF1 is expressed by activated monocytes and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts.
抗原信息
免疫原
Recombinant Protein: mouse AIF1 protein
抗原种属
Mouse
基因名称
AIF1
基因ID
11629
蛋白名称
Allograft inflammatory factor 1
Uniprot ID
O70200
功能
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
化学信息
分子量Theoretical: 16 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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