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Anti-STEAP1 Polyclonal Antibody

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货号 TMAB-13210

Anti-STEAP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 STEAP1。Anti-STEAP1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-STEAP1 Polyclonal Antibody

Anti-STEAP1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13210

Anti-STEAP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 STEAP1。Anti-STEAP1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-STEAP1 Polyclonal Antibody is a Rabbit antibody targeting STEAP1. Anti-STEAP1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Cow,Horse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endosome membrane; Multi-pass membrane protein.
组织特异性Ubiquitously expressed. Highly expressed in prostate tumors.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell cell junctions. Prostate cancer is the most frequently diagnosed cancer and is the second leading cause of cancer-related deaths in American men. Although the early serum detection of prostate-specific antigen (PSA) plays important roles in early diagnosis, it may not distinguish prostate cancer from benign diseases. Recently, a novel protein, which contains 339 amino acids, named STEAP (six transmembrane epithelial antigen of the prostate), was identified in advanced prostate cancer. STEAP is unique among the currently known prostate cancer markers because of its putative secondary structure, from which one may predict that it functions as a potential channel protein. STEAP is strongly expressed in advanced prostate cancer and some extent expression in other cancers, such as colon and ovarian cancer cell lines.
抗原信息
免疫原
KLH conjugated synthetic peptide: human STEAP1
抗原种属
Human
基因名称
STEAP1
基因ID
蛋白名称
Metalloreductase STEAP1
Uniprot ID
功能
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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