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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ZIC3 Polyclonal Antibody

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货号 TMAB-14320

Anti-ZIC3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ZIC3。Anti-ZIC3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ZIC3 Polyclonal Antibody

Anti-ZIC3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14320

Anti-ZIC3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ZIC3。Anti-ZIC3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-ZIC3 Polyclonal Antibody is a Rabbit antibody targeting ZIC3. Anti-ZIC3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Zic3 is a C2H2 zinc finger transcription factor that establishes a proper left-right axis and midline neural patterning during early development of the vertebrate embryo. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. Zic3 mutations in the zinc finger DNA binding domain and in the N-terminal domain result in loss of reporter gene transactivation, and mutations between amino acids 253-323 of the Zic3 protein causes aberrant cytoplasmic localization rather than the wild type nuclear localization.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ZIC3
抗原种属
Human
基因名称
ZIC3
基因ID
7547
蛋白名称
Zinc finger protein ZIC 3
Uniprot ID
O60481
功能
Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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