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TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregulin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 58.5 kDa and the accession number is Q8IYR6-1.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 μg | ¥ 386 | 6-8日内发货 | |
10 μg | ¥ 619 | 6-8日内发货 | |
20 μg | ¥ 987 | 5日内发货 | |
50 μg | ¥ 1,960 | 5日内发货 | |
100 μg | ¥ 3,380 | 5日内发货 |
生物活性 | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
产品描述 | TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregulin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 58.5 kDa and the accession number is Q8IYR6-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | Q8IYR6-1 |
别名 | transmembrane protein with EGF-like and two follistatin-like domains 1,TR-1,H7365,CT120.1,C9orf2 |
蛋白构建 | A DNA sequence encoding the human TMEFF1 (NP_003683.2) (Met1-Val330) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Ser 40 |
蛋白纯度 | > 85 % as determined by SDS-PAGE. |
分子量 | 58.5 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. |
研究背景 | TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. |