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Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3
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还可以产品编号 TMAB-10286
Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-ADAM17 (Thr735)。Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3
Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3
一键复制产品信息 还可以产品编号 TMAB-10286
Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-ADAM17 (Thr735)。Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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| 产品描述 | Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3 is a Rabbit antibody targeting Phospho-ADAM17 (Thr735). Anti-Phospho-ADAM17 (Thr735) Polyclonal Antibody 3 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse (predicted:Rat,Pig,Cow,Sheep) |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq]. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human ADAM17 around the phosphorylation site of Thr735 |
| 抗原种属 | Human |
| 基因名称 | ADAM17 |
| 基因ID | |
| 蛋白名称 | Disintegrin and metalloproteinase domain-containing protein 17 |
| Uniprot ID | |
| 功能 | Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway (By similarity). |
| 分子量 | Theoretical: 68/91 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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