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Anti-RBP4 Antibody-FITC (2J141)
还可以产品编号 TMAY-00680F
Anti-RBP4 Antibody-FITC (2J141) 是一种 FITC-conjugated Mouse 抗体，靶向 RBP4。Anti-RBP4 Antibody-FITC (2J141) 可用于 FCM。
Anti-RBP4 Antibody-FITC (2J141)
Anti-RBP4 Antibody-FITC (2J141)
还可以产品编号 TMAY-00680F
Anti-RBP4 Antibody-FITC (2J141) 是一种 FITC-conjugated Mouse 抗体，靶向 RBP4。Anti-RBP4 Antibody-FITC (2J141) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-RBP4 Antibody-FITC (2J141) is a FITC-conjugated Mouse antibody targeting RBP4. Anti-RBP4 Antibody-FITC (2J141) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2J141 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-RBP4 reactivity on HepG2 cells analyzed by flow cytometry. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with FITC conjugated Mouse anti-RBP4, The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RBP4 (rh RBP4; TMPY-00907; NP_006735.2; Met 1-Leu 201) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.1% sodium azide |
| 研究背景 | Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human RBP4 protein (TMPY-00907) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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