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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HDPTP Polyclonal Antibody

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货号 TMAB-06954

Anti-HDPTP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HDPTP。Anti-HDPTP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-HDPTP Polyclonal Antibody

Anti-HDPTP Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06954

Anti-HDPTP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HDPTP。Anti-HDPTP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-HDPTP Polyclonal Antibody is a Rabbit antibody targeting HDPTP. Anti-HDPTP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Pig)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Cytoplasmic vesicle. Endosome. Cytoplasm, cytoskeleton, cilium basal body.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景HD-PTP is a 1,636 amino acid protein encoded by the human gene PTPN23. HD-PTP belongs to the protein-tyrosine phosphatase family, non-receptor class subfamily. It contains one BRO1 domain, two TPR repeats and one tyrosine-protein phosphatase domain. The C-terminal region contains the PTP-like domain, whereas the N-terminal region contains the two TPR regions. These regions are homologous to the yeast protein, BRO1, which is involved in the mitogen-activated protein kinase signaling pathway. Similarly, HD-PTP is believed to act as a negative regulator of Ras-mediated mitogenic activity and is phosphorylated upon DNA damage, probably by ATM or ATR. HD-PTP protein is differentially modulated by two angiogenic growth factors. While Vascular Endothelial Growth Factor (VEGF) has no affect on protein levels, Fibroblast Growth Factor-2 (FGF-2) induces HD-PTP degradation via the proteasome system.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HDPTP
抗原种属
Human
基因名称
PTPN23
基因ID
25930
蛋白名称
Tyrosine-protein phosphatase non-receptor type 23
Uniprot ID
Q8N6Z5
功能
May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
化学信息
分子量Theoretical: 179 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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