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Anti-RNF13 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF13。Anti-RNF13 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-RNF13 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF13。Anti-RNF13 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-RNF13 Polyclonal Antibody is a Rabbit antibody targeting RNF13. Anti-RNF13 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane. Lysosome membrane. Nucleus inner membrane. Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane. |
| 组织特异性 | Widely expressed (at protein level). In normal pancreas, expressed in islets, but not in ducts, nor in acini (at protein level). |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF13 (ring finger protein 13), also known as RZF, FLJ93817 or MGC13689, is a novel 381 amino acid E3 ubiquitin ligase that localizes to the nucleus. RNF13 contains one RING-type zinc finger and the C-terminal portion of RNF13 has the ability to mediate ubiquitination. Recent studies suggest that RNF13 may be involved in the development of pancreatic cancer via ubiquitin-mediated modification of proteins. The gene encoding RNF13 maps to human chromsome 3q25.1, and a pseudogene (which is also located on chromosome 3), exists for this gene. |
| 免疫原 | KLH conjugated synthetic peptide: human RNF13 |
| 抗原种属 | Human |
| 基因名称 | RNF13 |
| 基因ID | |
| 蛋白名称 | E3 ubiquitin-protein ligase RNF13 |
| Uniprot ID | |
| 功能 | E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation. |
| 分子量 | Theoretical: 39 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |